Heart-on-a-Chip using Human Stem Cells

Cardiovascular diseases have been the world’s leading cause of death for nearly the past hundred years.

Heart on a chip research diagram

Human induced pluripotent stem cells (hiPSCs) have recently come to the forefront as a new tool to study human diseases in a more realistic model. Additionally, tissue engineering has advanced to a point where devices smaller than a penny can be used to study biology without the use of expensive animal models.

We aim to combine these two emerging technologies to engineer a 3D device that mimics both the beating myocardium and the vasculature of the human heart. We aim to use our device as a tool to study cardiovascular pathology, drugs, and treatments using a specific patients own hiPSCs for personalized treatment.