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The field of tissue engineering has established to the point where we are now in the position to build living micromachines. Such biomachines can be engineered to function autonomously, can be integrated into humans for regenerative medicine purposes or for body augmentation, or can be used as testing grounds for studying disease pathology and drugs’ effectiveness. Two main challenges for achieving such systems are (1) the ability to fabricate arbitrarily complex parts with desired biochemical and mechanical properties while maintaining cell viability and functionality and (2) vascularization, that will allow the components to nourish and communicate with one other.

In Zorlutuna Lab, we use tissue engineering, biomimetic materials, microfabrication, stem cells and genetic engineering to address these issues. Such bio-inspired systems will have impact not only on tissue regeneration applications, but also potentially on emerging fields of research in bioengineering, ranging from bio-robotics to disease modeling.